Severity of Intracranial Large Artery Disease Correlates With Cerebral Small Vessel Disease

Background Small vessel disease (SVD) shares common vascular risk factors with large artery disease (LAD). However, little is known about the relationship between intracranial artery stenosis and SVD burden. Purpose To investigate whether SVD burden correlates with severity of intracranial LAD. Study Type Retrospective. Population Five hundred and sixteen patients with LAD of arterial circulation were enrolled from one hospital, including 384 males (59 ± 11 years) and 132 females (60 ± 12 years). Field Strength/Sequence 3 T. T1‐weighted fast spin echo (T1W FSE), T2W FSE, T2 fluid attenuated inversion recovery, diffusion‐weighted imaging, susceptibility‐weight imaging, and time‐of‐flight magnetic resonance angiography. Assessment The LAD was divided into mild stenosis (