Risk Assessment of Nine Coccidiostats in Commercial and Home Raised Poultry

For the first time, this paper aimed to evaluate nine ionophore and synthetic coccidiostat residues in poultry muscle samples, obtained from different production types, by solid–liquid extraction followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The fully validated methodol...

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Veröffentlicht in:Journal of agricultural and food chemistry 2021-12, Vol.69 (47), p.14287-14293
Hauptverfasser: Martins, Rui R, Azevedo, Vanessa S, Pereira, André M. P. T, Silva, Liliana J. G, Duarte, Sofia C, Pena, Angelina
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Sprache:eng
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Zusammenfassung:For the first time, this paper aimed to evaluate nine ionophore and synthetic coccidiostat residues in poultry muscle samples, obtained from different production types, by solid–liquid extraction followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The fully validated methodology was successfully applied to a total of 101 chicken and turkey samples obtained from canteens, supermarkets, and home productions in Portugal. Halofuginone, diclazuril, decoquinate, narasin, lasalocid, and salinomycin were detected in 20.8% of the samples. Home raised samples showed a greater frequency, 47.1%. The synthetic coccidiostats halofuginone, diclazuril, and decoquinate were found in averages of 0.7 μg kg–1,2.9 μg kg–1, and 3.7 μg kg–1, respectively, while averages of 1.2 μg kg–1, 1.6 μg kg–1, and 1.3 μg kg–1 were found regarding the ionophores narasin, lasalocid, and salinomycin. As for the risk assessment, values lower than 8.06% of the acceptable daily intake (ADI) were observed, indicating that exposure to coccidiostats through consumption of poultry meat does not represent risk to consumers.
ISSN:0021-8561
1520-5118
DOI:10.1021/acs.jafc.1c05656