The use of sugammadex in an infant with prolonged neuromuscular blockade - A case report

BACKGROUNDResidual neuromuscular blockade (RNMB) is a frequent event after general anesthesia, which can lead to serious complications, such as upper airway obstruction. Sugammadex is useful in reversing RNMB. However, its use in infants has not yet been approved by the Food and Drug Administration....

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Veröffentlicht in:Anesthesia and pain medicine 2022, Vol.17 (1), p.52-56
Hauptverfasser: Kim, Hyunho, Cho, Joonho, Lee, Sangseok, Lim, Yunhee, Yoo, Byunghoon
Format: Report
Sprache:eng
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Zusammenfassung:BACKGROUNDResidual neuromuscular blockade (RNMB) is a frequent event after general anesthesia, which can lead to serious complications, such as upper airway obstruction. Sugammadex is useful in reversing RNMB. However, its use in infants has not yet been approved by the Food and Drug Administration. Therefore, anesthesiologists can be hesitant use it, even in situations where no other choice is available. CASEA two-month-old baby presented to the hospital for umbilical polypectomy. At the end of the surgery, neostigmine was administered. Even after waiting for 30 min and injecting an additional dose of neostigmine, neuromuscular blockade was not adequately reversed. Eventually, sugammadex was administered, and spontaneous breathing returned. CONCLUSIONSIf there were no particular causes of delayed return to spontaneous breathing in infants, RNMB should be considered and reversal with sugammadex would be useful.
ISSN:2383-7977
DOI:10.17085/apm.21071