The role of adropin, HIF-1α and apelin biomarkers in the diagnosis of acute mesentaric ischemia

The absence of a specific biomarker for acute mesenteric ischemia diagnosis results in a delay in diagnosis and treatment, as well as a high mortality rate. The current research examined whether the proteins adropin, HIF-1α, and apelin may be used to help in the early detection of acute mesenteric i...

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Veröffentlicht in:The American journal of emergency medicine 2022-01, Vol.51, p.223-227
Hauptverfasser: Kurt, Engin, Tekin, Erdal, Kurt, Nezahat, Bayramoglu, Atif
Format: Artikel
Sprache:eng
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Zusammenfassung:The absence of a specific biomarker for acute mesenteric ischemia diagnosis results in a delay in diagnosis and treatment, as well as a high mortality rate. The current research examined whether the proteins adropin, HIF-1α, and apelin may be used to help in the early detection of acute mesenteric ischemia. A total of 20 patients with acute mesenteric ischemia, 20 patients with abdominal pain, and 20 healthy controls were included in the study. The levels of adropin, HIF-1, and apelin in the serum were determined using the ELISA method. Adropin concentrations were significantly higher in the acute mesenteric ischemia group than in the abdominal pain and healthy control groups (p 
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2021.10.058