Surface-functionalized curcumin-loaded polymeric nanocapsules could block apomorphine-induced behavioral changes in rats

Background Surface functionalization enhances the properties and characteristics of polymeric nanocapsules (NCs) mainly due to the surface charge, surfactants, and polymer coating type. Curcumin (CUR) is a bioactive compound with several proven pharmacological properties and low bioavailability. Thi...

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Veröffentlicht in:	Pharmacological reports 2022-02, Vol.74 (1), p.135-147
Hauptverfasser:	de Oliveira Pacheco, Camila, de Gomes, Marcelo Gomes, da Silva Neto, Manoel Rodrigues, Parisotto, Alcides José Martins, dos Santos, Renata Bem, Maciel, Tamara Ramos, Ribeiro, Ana Cláudia Funguetto, Giacomeli, Renata, Haas, Sandra Elisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apomorphine - pharmacology Behavior, Animal - drug effects Curcumin - pharmacology Dopamine Agonists - pharmacology Drug Safety and Pharmacovigilance Enzyme Inhibitors Hexoses - pharmacology Medicine Nanocapsules - chemistry Pharmacotherapy Pharmacy Plants, Medicinal Rats Stereotyped Behavior - drug effects Treatment Outcome Vitamin E - pharmacology
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