Post‐castration prostatic involution: A morphometric and endocrine study of healthy canines and those with benign prostatic hyperplasia

The objective of this study was to evaluate the effect of castration on dimensions of the prostate by B‐mode ultrasound for 90 days, as well as to evaluate changes in serum concentrations of testosterone and oestradiol in clinically healthy canines and those with benign prostatic hyperplasia (BPH). Three groups of animals were used: healthy canines castrated on day 0 (HCC, n = 8), canines with a diagnosis of benign prostatic hyperplasia (BPHC, n = 9) castrated on day 0 and healthy uncastrated canines (IHCC, n = 10). Prostate size was obtained by B‐mode ultrasound, while blood samples were collected (days 0, 7, 14, 28, 60 and 90 post‐castration) to determine the serum testosterone and oestradiol concentration. Castration did not affect serum oestradiol concentrations. Castration led to a decrease in serum testosterone (reaching values