Comprehensive blood coagulation potential in patients with acquired hemophilia A: retrospective analyses of plasma samples obtained from nationwide centers across Japan

Global coagulation potential was assessed in 59 patients with acquired hemophilia A (PwAHA) by clot waveform analysis (CWA) and/or thrombin and plasmin generation assay. Relationships between factor VIII activity (FVIII:C) and the parameters from CWA and T/P-GA in patients with congenital HA were co...

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Veröffentlicht in:	International journal of hematology 2022-02, Vol.115 (2), p.163-172
Hauptverfasser:	Takeyama, Masahiro, Sasai, Kana, Matsumoto, Tomoko, Furukawa, Shoko, Ogiwara, Kenichi, Yada, Koji, Onishi, Tomoko, Shima, Midori, Nogami, Keiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Blood Coagulation Blood Coagulation Tests Child Coagulation Coagulation factors Female Hematology Hemophilia Hemophilia A - blood Hemophilia A - epidemiology Humans Immunosuppression Japan - epidemiology Male Medicine Medicine & Public Health Middle Aged Oncology Original Article Parameters Patients Plasmin Retrospective Studies Thrombin Waveforms Young Adult
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Zusammenfassung:	Global coagulation potential was assessed in 59 patients with acquired hemophilia A (PwAHA) by clot waveform analysis (CWA) and/or thrombin and plasmin generation assay. Relationships between factor VIII activity (FVIII:C) and the parameters from CWA and T/P-GA in patients with congenital HA were compared by grading coagulation potential related to FVIII:C: T1 (FVIII:C
ISSN:	0925-5710 1865-3774
DOI:	10.1007/s12185-021-03249-w