Sarcopenia at the infrahyoid level as a prognostic factor in patients with advanced-stage non-virus-related head and neck carcinoma

Purpose The purpose of this study was to assess whether the infrahyoid skeletal muscle index (IHSMI) can be used instead of the L3 skeletal muscle index (L3SMI) to define sarcopenia and predict prognosis in patients with locally advanced head and neck squamous cell carcinoma (LHNSCC). Methods Patien...

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Veröffentlicht in:	European archives of oto-rhino-laryngology 2022-06, Vol.279 (6), p.3131-3137
Hauptverfasser:	Yunaiyama, Daisuke, Okubo, Mitsuru, Arizono, Eri, Tsukahara, Kiyoaki, Tanigawa, Maki, Nagao, Toshitaka, Saito, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Female Head and Neck Head and Neck Neoplasms - complications Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Head and Neck Surgery Humans Male Medicine Medicine & Public Health Muscle, Skeletal Neurosurgery Otorhinolaryngology Prognosis Retrospective Studies Sarcopenia - diagnostic imaging Sarcopenia - etiology Squamous Cell Carcinoma of Head and Neck - pathology
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Zusammenfassung:	Purpose The purpose of this study was to assess whether the infrahyoid skeletal muscle index (IHSMI) can be used instead of the L3 skeletal muscle index (L3SMI) to define sarcopenia and predict prognosis in patients with locally advanced head and neck squamous cell carcinoma (LHNSCC). Methods Patients treated for LHNSCC between January 2009 and April 2018 were assessed. The muscular area at the L3 transverse process and infrahyoid was contoured on absorption-corrected computed tomography prior to treatment. Sarcopenia based on L3SMI (S-L) was defined as values of
ISSN:	0937-4477 1434-4726
DOI:	10.1007/s00405-021-07147-z