High RSK4 expression constitutes a predictor of poor prognosis for patients with clear cell renal carcinoma

This research focuses on exploring RSK4 protein expression within Clear Cell Renal Cell Carcinoma (ccRCC), based on these investigations on level of expressions coupled with the relevance to clinicopathologic features and clinical outcomes. The expression of RSK4 in 48 ccRCC and 20 hydronephrosis sa...

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Veröffentlicht in:Pathology, research and practice research and practice, 2021-11, Vol.227, p.153642-153642, Article 153642
Hauptverfasser: Ma, Jing, Wang, Kaijing, Chai, Jia, Xu, Tianqi, Wei, Jie, Liu, Yixiong, Wang, Yangang, Xu, Junpeng, Li, Mingyang, Fan, Linni
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Sprache:eng
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Zusammenfassung:This research focuses on exploring RSK4 protein expression within Clear Cell Renal Cell Carcinoma (ccRCC), based on these investigations on level of expressions coupled with the relevance to clinicopathologic features and clinical outcomes. The expression of RSK4 in 48 ccRCC and 20 hydronephrosis samples were under the detection of immunohistochemistry; besides, its relevance to the combination of clinicopathologic features with prognosis was committed in virtue of statistical approaches. The 48 ccRCC samples included 36 (75%, 36/48) positive for RSK4, while the positive rate in hydronephrosis samples were 5 (25%, 5/20). Statistical analysis showed that RSK4 in ccRCC samples express higher expression the hydronephrosis samples (P 
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2021.153642