Association between lung compliance phenotypes and mortality in COVID-19 patients with acute respiratory distress syndrome

Association between lung compliance phenotypes and mortality in COVID-19 patients with acute respiratory distress syndrome

ABSTRACT Introduction: Acute respiratory distress syndrome (ARDS) in COVID-19 is associated with a high mortality rate, though outcomes of the different lung compliance phenotypes are unclear. We aimed to measure lung compliance and examine other factors associated with mortality in COVID-19 patient...

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Veröffentlicht in:Annals of the Academy of Medicine, Singapore Singapore, 2021-09, Vol.50 (9), p.686-694
Hauptverfasser: Puah, Ser Hon, Cove, Matthew Edward, Phua, Jason, Kansal, Amit, Venkatachalam, Jonathen, Ho, Vui Kian, Sewa, Duu Wen, Gokhale, Roshni Sadshiv, Liew, Mei Fong, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Abisheganaden, John A, Leo, Yee Sin, Young, Barnaby Edward, Lye, David Chien, Yeo, Tsin Wen
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Sprache:eng
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Zusammenfassung:ABSTRACT Introduction: Acute respiratory distress syndrome (ARDS) in COVID-19 is associated with a high mortality rate, though outcomes of the different lung compliance phenotypes are unclear. We aimed to measure lung compliance and examine other factors associated with mortality in COVID-19 patients with ARDS. Methods: Adult patients with COVID-19 ARDS who required invasive mechanical ventilation at 8 hospitals in Singapore were prospectively enrolled. Factors associated with both mortality and differences between high (
ISSN:0304-4602
0304-4602
DOI:10.47102/annals-acadmedsg.2021129