A comparative study of efficacy and safety of autologous fat grafting versus Platelet‐rich plasma in the treatment of post‐acne scars

Background Platelet‐rich plasma is a useful adjuvant therapy in the treatment of acne scars. Fat is as ideal soft tissue filler. Aims To compare the efficacy and safety of subcision with autologous fat grafting versus subcision with intradermal Platelet‐rich plasma for the treatment of acne scars. Methods Twenty‐four patients were divided into two groups with 12 patients each. One group subjected to single session of subcision with autologous fat grafting. Second group treated with subcision followed by intradermal Platelet‐rich plasma monthly once for 3 months. High resolution digital photographs taken before and after every session. Single blinded physician assessment was also done. Results In quantitative acne scar assessment scoring, both group of patients showed significant percentage of improvement in acne scars, 61.23 ± 9.48% in patients treated with subcision followed by autologous fat grafting and 44.16 ± 7.28% in patients treated with subcision followed by intradermal PRP. At the time of enrolment, 33.3% (n = 8) of patients had Grade A (milder) scarring, 50% (n = 12) had Grade B (moderate) scarring while 16.7% (n = 4) had Grade C (severe) scarring. After the completion of the treatment, it was found that 75% (n = 18) of patients were in Grade A while 20.8% (n = 5) of patients were in Grade B (p