Sodium arsenate induced genotoxicity, morphometric and morphological changes in mice embryo and protective role of Moringa oleifera extracts

The present study was carried out to find the comparative ameliorative role of Moringa oleifera leaf and flower extracts against sodium arsenate induced genotoxic, morphometric and morphological changes in mice embryo. Seven to eight week old pregnant females (N=44) with body weight of 20-25g at ges...

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Veröffentlicht in:Pakistan journal of pharmaceutical sciences 2021-05, Vol.34 (3(Supplementary)), p.1031-1037
Hauptverfasser: Ali, Kashif, Iqbal, Asia, Saleem, Maham, Riaz, Ayesha, Abbas, Sumaira, Arshad, Madeeha, Iqbal, Javed, Farhan Nasir, Muhammad, Bukhari, Syed Mohsin, Mahmud, Athar, Amin, Fareeha, Dastgir, Ghulam, Sughra, Fatima
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Sprache:eng
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Zusammenfassung:The present study was carried out to find the comparative ameliorative role of Moringa oleifera leaf and flower extracts against sodium arsenate induced genotoxic, morphometric and morphological changes in mice embryo. Seven to eight week old pregnant females (N=44) with body weight of 20-25g at gestation day zero were divided randomly in groups (A, B, C, D, E, F, G, H, I, J and K). Group A was of control while all others were experimental groups and administered with selected doses of sodium arsenate as toxicant (6mg/kg B.W and 12mg/kg/B.W) and Moringa oleifera leaf and flower extracts as antidote (150mg/kg and 300mg/kg B.W). Significant (p
ISSN:1011-601X
DOI:10.36721/PJPS.2021.34.3.SUP.1031-1037.1