The assessment of Tp‐e interval and Tp‐e/QT ratio in patients with hyperthyroidism before and after thyroid surgery

Background Ventricular repolarisation is assessed using the Tp‐e interval and QT interval corrected by the heart rate (QTc) via an electrocardiogram (ECG). Prolonged Tp‐e/QTc is related with an increased risk of arrhythmias and cardiac mortality. Objective This study was conducted at a single centre in collaboration with general surgery and cardiology clinics. We aimed to appraise the assessment of Tp‐e interval and Tp‐e/QT ratio in patients with hyperthyroidism before and after thyroid surgery. Methods Totally 65 patients with hyperthyroidism before and after thyroid surgery were enrolled in our study. In presurgical hospitalisation and six months after the thyroid surgery, we measured the electrocardiographic parameters again on same patients. All subjects who were investigated in this study were in sinus rhythm. Tp‐e interval, Tp‐e/QT and Tp‐e/QTc ratios were measured from the 12‐lead electrocardiogram. Results Heart rate (P = .073), QT interval (P = .432) and QTc interval (P = .179) were similar before and after thyroid surgery. Tp‐e interval (84.6 ± 13.1 vs 77.2 ± 10.9; P = .031), Tp‐e/QT ratio (0.23 ± 0.04 vs 0.21 ± 0.04; P