Influence of Vitamin A Status on the Choice of Sampling Time for Application of the Retinol Isotope Dilution Method in Theoretical Children

Influence of Vitamin A Status on the Choice of Sampling Time for Application of the Retinol Isotope Dilution Method in Theoretical Children

Vitamin A status may influence the choice of a blood sampling time for applying the retinol isotope dilution (RID) equation to predict vitamin A total body stores (TBS) in children. We aimed to identify time(s) after administration of labeled vitamin A that provide accurate estimates of TBS in theor...

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Veröffentlicht in:The Journal of nutrition 2021-12, Vol.151 (12), p.3874-3881
Hauptverfasser: Lopez-Teros, Veronica, Green, Michael H, Haskell, Marjorie J, Green, Joanne Balmer
Format: Artikel
Sprache:eng
Schlagworte:
Child
Children
Dilution
Humans
Indicator Dilution Techniques
Isotope dilution method
Isotopes
mathematical modeling
Models, Biological
Nutritional Status
Plasma
Retinene
retinol isotope dilution
Sampling
Specimen Handling
Stores
Vitamin A
Vitamin A Deficiency
vitamin A status in children
vitamin A total body stores
Vitamin deficiency
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Zusammenfassung:Vitamin A status may influence the choice of a blood sampling time for applying the retinol isotope dilution (RID) equation to predict vitamin A total body stores (TBS) in children. We aimed to identify time(s) after administration of labeled vitamin A that provide accurate estimates of TBS in theoretical children with low or high TBS. We postulated 2- to 5-y-old children (12/group) with low (
ISSN:0022-3166
1541-6100
DOI:10.1093/jn/nxab310