Comparing Seizure‐Related Death and Suicide in Younger Adults with Epilepsy

Comparing Seizure‐Related Death and Suicide in Younger Adults with Epilepsy

Younger adults with epilepsy have an increased mortality. Some deaths are seizure‐related, for example, sudden unexpected death in epilepsy (SUDEP), whereas others, for example, suicide, have multiple causes, including adverse effects of the treatment on mood. In this retrospective population‐based...

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Veröffentlicht in:Annals of neurology 2021-12, Vol.90 (6), p.983-987
Hauptverfasser: Kløvgaard, Marius, Lynge, Thomas H., Tsiropoulos, Ioannis, Uldall, Peter V., Banner, Jytte, Winkel, Bo G., Ryvlin, Philippe, Tfelt‐Hansen, Jacob, Sabers, Anne
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Adults
Cause of Death
Convulsions & seizures
Death
Epilepsy
Epilepsy - mortality
Female
Humans
Male
Middle Aged
Mortality
Population studies
Retrospective Studies
Risk Factors
Seizures
Seizures - mortality
Sudden Unexpected Death in Epilepsy
Suicide
Suicide - statistics & numerical data
Young Adult
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Zusammenfassung:Younger adults with epilepsy have an increased mortality. Some deaths are seizure‐related, for example, sudden unexpected death in epilepsy (SUDEP), whereas others, for example, suicide, have multiple causes, including adverse effects of the treatment on mood. In this retrospective population‐based study of all Danish persons with epilepsy aged 18 to 49 years during 2007 to 2009 we evaluated the risk of death from seizures and suicide. SUDEP comprised 82.7% of all seizure‐related death. Younger adults with epilepsy had an 8.3‐fold increased risk of death from seizure‐related causes compared with suicide. This underpins the importance of effective seizure control in preventing premature death. ANN NEUROL 2021;90:983–987
ISSN:0364-5134
1531-8249
DOI:10.1002/ana.26227