Traumatic cervical spinal cord injury: relationship of MRI findings to initial neurological impairment

Purpose To quantify the degree of available space for the cord and cord swelling in patients following traumatic cervical spinal cord injury (TCSCI), and to assess the relationship among the available space for the cord, cord swelling, and the severity of neurological impairment. Methods This study included 91 patients. The following indexes were measured by two blinded observers: maximum cord available area (CAA max ) and maximum cord swelling area (CSA max ). The American Spinal Injury Association (ASIA) impairment scale (AIS) grades were used to evaluate the extent of neurological injury. Relationship among CAA max , CSA max , and initial AIS grades was assessed via univariate and multivariate analyses. Results Patients who were AIS grade A (complete injury) demonstrated significantly greater median CAA max and CSA max than AIS grade C or D (incomplete injury) ( P 38%) and cord swelling (CSA max > 29%) can be used to identify patients at risk for TCSCI and both imaging characteristics are associated with an increased likelihood of severe neurological deficits. Level of evidence Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.