Management experience of pediatric meningioma in a Mexican reference center

Determine the histopathological and clinical characteristics of patients diagnosed with meningiomas and to establish the frequency of these tumors in the pediatric population Mexican. Determine the NF1/2 frequency in meningioma pediatric. Samples from the histopathology file were reviewed, and from the complete clinical file the following patient data was reviewed: age, gender, diagnosis, diagnosis year, surgical resection, location, tumor size, symptoms, and family background. The frequency of NF1/2 in pediatric meningioma was reviewed in literature. Forty-four de novo cases were collected from pediatric patients; 19 were female patients and 25 males. The most frequent histological subtype was transitional meningioma. Of all the cases, 75% had a supratentorial localization and 20% had an extramedullary intrarachidian localization. Some clinical manifestations included seizures, paresis, headache, and visual disturbances. There is a low incidence of meningiomas in the pediatric population, more than 70% are Grade I, and they have supratentorial localization. •Pediatric meningiomas have a low incidence in the Mexican population.•Seventy percent of meningiomas are supratentorial.•In pediatric patients NF1 and NF2 are found in 19% and 8%, respectively.•NF1 and NF2 contribute significantly to morbidity and mortality.