Safety and efficacy of minimalist transcatheter aortic valve implantation using a new-generation balloon-expandable transcatheter heart valve in bicuspid and tricuspid aortic valves

Background Bicuspid aortic valve may be associated with increased complications during transcatheter aortic valve implantation (TAVI). Aims Compare balloon-expandable transcatheter heart valve (THV) safety and efficacy in severe tricuspid (TAV) and bicuspid (BAV) aortic stenosis. Methods Transfemora...

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Veröffentlicht in:Clinical research in cardiology 2021-12, Vol.110 (12), p.1993-2006
Hauptverfasser: Michel, Jonathan M., Frangieh, Antonio H., Giacoppo, Daniele, Alvarez-Covarrubias, Hector A., Pellegrini, Costanza, Rheude, Tobias, Deutsch, Oliver, Mayr, N. Patrick, Rumpf, P. Moritz, Stähli, Barbara E., Kastrati, Adnan, Schunkert, Heribert, Xhepa, Erion, Joner, Michael, Kasel, A. Markus
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Sprache:eng
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Zusammenfassung:Background Bicuspid aortic valve may be associated with increased complications during transcatheter aortic valve implantation (TAVI). Aims Compare balloon-expandable transcatheter heart valve (THV) safety and efficacy in severe tricuspid (TAV) and bicuspid (BAV) aortic stenosis. Methods Transfemoral TAVI was performed in 743 patients (Jan 2014–June 2019) using the SAPIEN 3 THV. Aortic valve morphology was determined using computed tomography. Valve Academic Research Consortium-2 (VARC-2) derived safety and efficacy endpoints at 1 year were evaluated. Results BAV patients ( n  = 78), were younger (77 [72, 81] vs. 81 [78, 85] years, p  
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-021-01935-7