Analysis of corneal densitometry and endothelial morphometry in patients with psoriasis

•Regular eye examination is crucial in patients with psoriasis, for early detection and management of ocular involvement.•Corneal changes especially endothelial alterations can be important in patients with psoriasis.•Psoriasis could lead to dry eye disease. To evaluate corneal endothelial properties and corneal densitometry values in patients with psoriasis and to compare the results with those of healthy controls. This prospective, comparative, and cross-sectional study included 106 eyes of 53 patients who were diagnosed with psoriasis and 106 eyes of 53 age-gender matched healthy controls. All patients were evaluated in terms of ocular surface tests such as Schirmer-1 and tear break-up time (TBUT). Corneal endothelial measurements were performed using noncontact specular microscopy. Corneal tomographic and densitometric measurements were obtained using the Scheimpflug imaging system. Measurements were also evaluated according to the psoriasis area and severity index (PASI) score. The mean TBUT and Schirmer 1 test values were significantly lower in the psoriasis group than in the healthy controls (p = 0.02, p