New technologies for improved relevance in miRNA research

New technologies for improved relevance in miRNA research

After a number of years of research in the field of miRNA, the robustness and biological relevance of many published articles is increasingly being questioned. We propose the use of new RNA-seq approaches, genome editing technologies, and updated public databases to improve the quality, reliability,...

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Veröffentlicht in:Trends in genetics 2021-12, Vol.37 (12), p.1060-1063
Hauptverfasser: Jacquet, Karine, Vidal-Cruchez, Olivia, Rezzonico, Roger, Nicolini, Victoria J., Mograbi, Baharia, Hofman, Paul, Vassaux, Georges, Mari, Bernard, Brest, Patrick
Format: Artikel
Sprache:eng
Schlagworte:
CRISPR
CRISPR-Cas Systems
Gene Editing
genome editing
microRNA
MicroRNAs - genetics
noncoding RNA
Reproducibility of Results
RNA sequencing
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Beschreibung
Zusammenfassung:After a number of years of research in the field of miRNA, the robustness and biological relevance of many published articles is increasingly being questioned. We propose the use of new RNA-seq approaches, genome editing technologies, and updated public databases to improve the quality, reliability, and relevance of published data.
ISSN:0168-9525
DOI:10.1016/j.tig.2021.08.006