The effect of Gymnema sylvestre supplementation on glycemic control in type 2 diabetes patients: A systematic review and meta‐analysis

The effect of Gymnema sylvestre supplementation on glycemic control in type 2 diabetes patients: A systematic review and meta‐analysis

This systematic review and meta‐analysis aims to find the effect of Gymnema sylvestre (GS) supplementation on glycemic control in type‐2 diabetes mellitus (T2DM). PubMed, Cochrane library, Google Scholar, and Science Direct were searched from inception to June 2020 to identify the studies that repor...

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Veröffentlicht in:Phytotherapy research 2021-12, Vol.35 (12), p.6802-6812
Hauptverfasser: Devangan, Suneel, Varghese, Bincy, Johny, Ebin, Gurram, Surender, Adela, Ramu
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Blood Glucose
Cholesterol
Complications
Confidence intervals
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - drug therapy
Dietary Supplements
Glucose
Glycated Hemoglobin A - analysis
Glycemic Control
Gymnema sylvestre
Hemoglobin
Humans
lipid profile
Lipids
Meta-analysis
Parameter identification
Search engines
Supplements
Systematic review
Triglycerides
type‐2 DM
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Zusammenfassung:This systematic review and meta‐analysis aims to find the effect of Gymnema sylvestre (GS) supplementation on glycemic control in type‐2 diabetes mellitus (T2DM). PubMed, Cochrane library, Google Scholar, and Science Direct were searched from inception to June 2020 to identify the studies that reported GS supplementation on glycemic parameters. Standardized mean difference (SMD) was calculated by comparing the post‐intervention data with baseline data. SMDs with 95% confidence intervals (CIs) were pooled using a random‐effects model. Our meta‐analysis consisting of 10 studies with a total of 419 participants showed that GS supplementation significantly reduces fasting blood glucose (FBG) (SMD 1.57 mg/dl, 95% CI 2.22 to −0.93, p 
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.7265