The Association Between D-dimer Levels and Long-Term Neurological Outcomes of Patients with Traumatic Brain Injury: An Analysis of a Nationwide Observational Neurotrauma Database in Japan

Background We evaluated the association between D-dimer (DD) levels and long-term neurological prognoses among patients with isolated traumatic brain injury. Methods Using data from multiple centers in the Japanese Neurotrauma Data Bank, we conducted an observational retrospective cohort study. Pati...

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Veröffentlicht in:	Neurocritical care 2022-04, Vol.36 (2), p.483-491
Hauptverfasser:	Fujiwara, Gaku, Okada, Yohei, Sakakibara, Takehiko, Yamaki, Tarumi, Hashimoto, Naoya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Aged Anticoagulants Blood pressure Brain Injuries, Traumatic - complications Brain Injuries, Traumatic - therapy Classification Coma Critical Care Medicine Fibrin Fibrinogen Degradation Products Glasgow Outcome Scale Humans Intensive Internal Medicine Japan - epidemiology Medical prognosis Medicine Medicine & Public Health Middle Aged Mortality Neurology Neurosurgery Original Work Patients Regression analysis Retrospective Studies Tomography Trauma Traumatic brain injury Treatment Outcome
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Zusammenfassung:	Background We evaluated the association between D-dimer (DD) levels and long-term neurological prognoses among patients with isolated traumatic brain injury. Methods Using data from multiple centers in the Japanese Neurotrauma Data Bank, we conducted an observational retrospective cohort study. Patients with isolated traumatic brain injury (head Abbreviated Injury Scale score > 2; any other Abbreviated Injury Scale score
ISSN:	1541-6933 1556-0961
DOI:	10.1007/s12028-021-01329-7