Time to remove hypertension from our vocabulary?
Using the same methodological–analytical approach as in previous BPLTTC meta-analyses,2–5 the authors report similar relative reductions in major cardiovascular events from blood pressure lowering across a wide range of pre-treatment blood pressure levels, at least down to 120/70 mm Hg, within a wid...
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Veröffentlicht in: | The Lancet (British edition) 2021-09, Vol.398 (10305), p.1023-1025 |
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Sprache: | eng |
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Zusammenfassung: | Using the same methodological–analytical approach as in previous BPLTTC meta-analyses,2–5 the authors report similar relative reductions in major cardiovascular events from blood pressure lowering across a wide range of pre-treatment blood pressure levels, at least down to 120/70 mm Hg, within a wide range of age groups, up to 85 years and older. In 2002, the 1-million participant Prospective Studies Collaboration reported that the relative difference in risk of vascular mortality for a given difference in blood pressure was about the same across a blood pressure range from over 170/100 mm Hg down to at least 115/75 mm Hg.8 These findings suggested that the most meaningful definition of hypertension, for people aged 40–89 years, might be a blood pressure as low as 115/75 mm Hg—ie, the level above which risk of vascular disease increases monotonically with increasing blood pressure. [...]it is reassuring that all-cause mortality was not increased in treated people aged 85 years and older, supporting the common practice of continuing blood pressure-lowering treatment in these patients, unless other good reasons not to exist. Because most people aged 40 years and older have blood pressure levels above 115/75 mm Hg,9 almost all middle-aged and older people therefore have hypertension, making the term meaningless or implying that they should all be recommended for antihypertensive treatment. |
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ISSN: | 0140-6736 1474-547X |
DOI: | 10.1016/S0140-6736(21)01916-4 |