Maternal Vaccination and Infant Influenza and Pertussis

BACKGROUND AND OBJECTIVES Infant influenza and pertussis disease causes considerable morbidity and mortality worldwide. We examined the effectiveness of maternal influenza and pertussis vaccines in preventing these diseases in infants. METHODS This inception cohort study comprised women whose pregna...

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Veröffentlicht in:Pediatrics (Evanston) 2021-09, Vol.148 (3), p.1
Hauptverfasser: Rowe, Stacey L., Leder, Karin, Perrett, Kirsten P., Romero, Nicole, Nolan, Terry M., Stephens, Nicola, Cowie, Benjamin C., Cheng, Allen C.
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Sprache:eng
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Zusammenfassung:BACKGROUND AND OBJECTIVES Infant influenza and pertussis disease causes considerable morbidity and mortality worldwide. We examined the effectiveness of maternal influenza and pertussis vaccines in preventing these diseases in infants. METHODS This inception cohort study comprised women whose pregnancies ended between September 1, 2015, and December 31, 2017, in Victoria, Australia. Maternal vaccination status was sourced from the Victorian Perinatal Data Collection and linked to 5 data sets to ascertain infant outcomes and vaccination. The primary outcome of interest was laboratory-confirmed influenza or pertussis disease in infants aged
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2021-051076