Case 26-2021: A 49-Year-Old Man with Relapsed Acute Myeloid Leukemia

Case 26-2021: A 49-Year-Old Man with Relapsed Acute Myeloid Leukemia

A 49-year-old man was evaluated because of relapsed acute myeloid leukemia that occurred 14 months after the initial diagnosis and treatment. Molecular genetic profiling at the time of relapse identified a new internal tandem duplication mutation in FLT3 ( FLT3 -ITD). A bone marrow biopsy was perfor...

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Veröffentlicht in:The New England journal of medicine 2021-08, Vol.385 (9), p.834-843
Hauptverfasser: Brunner, Andrew M, Newcomb, Richard A, Chen, Yi-Bin, Crabbe, Andrew M
Format: Artikel
Sprache:eng
Schlagworte:
Acute myeloid leukemia
Biopsy
Bone marrow
Bone Marrow Transplantation
Cancer
Cardiovascular disease
Case reports
Chemotherapy
Clinical Practice
Flow cytometry
Gallbladder diseases
Genetics
Hematology
Hospitalist
Hospitals
Laboratories
Leukemia
Lymphoma
Mens health
Mutation
Myeloid leukemia
Oncology
Patients
Primary Care
Stem cell transplantation
Treatments in Oncology
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Zusammenfassung:A 49-year-old man was evaluated because of relapsed acute myeloid leukemia that occurred 14 months after the initial diagnosis and treatment. Molecular genetic profiling at the time of relapse identified a new internal tandem duplication mutation in FLT3 ( FLT3 -ITD). A bone marrow biopsy was performed, and management decisions were made.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMcpc2103458