Tying peptide ropes

Although the natural lasso peptide microcin J25 remains an elusive target for total chemical synthesis itself, this topologically non-trivial building block has now been used to construct a range of interlocked molecular architectures including rotaxanes, catenanes and daisy chains.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature chemistry 2021-09, Vol.13 (9), p.822-823
1. Verfasser:	van Maarseveen, Jan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	639/638/541/964 639/638/549 639/638/92/611 Analytical Chemistry Biochemistry Chemical synthesis Chemistry Chemistry and Materials Science Chemistry, Multidisciplinary Chemistry/Food Science Inorganic Chemistry Microcin J25 Molecular structure News & Views news-and-views Organic Chemistry Peptides Physical Chemistry Physical Sciences Rotaxanes Science & Technology
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Beschreibung
Zusammenfassung:	Although the natural lasso peptide microcin J25 remains an elusive target for total chemical synthesis itself, this topologically non-trivial building block has now been used to construct a range of interlocked molecular architectures including rotaxanes, catenanes and daisy chains.
ISSN:	1755-4330 1755-4349
DOI:	10.1038/s41557-021-00771-6