TIM4+ adipose tissue-resident macrophages: new modulators of adiposity
Adipose tissue macrophages (ATMs) have important roles in the regulation of inflammatory responses and insulin resistance in obesity. A new study reports that a subpopulation of ATMs, TIM4 + resident ATMs, modulate adipocyte size via platelet-derived growth factor-CC production during development an...
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| Veröffentlicht in: | Nature reviews. Endocrinology 2021-11, Vol.17 (11), p.645-646 |
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| container_title | Nature reviews. Endocrinology |
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| creator | Huh, Jin Young Kim, Jae Bum |
| description | Adipose tissue macrophages (ATMs) have important roles in the regulation of inflammatory responses and insulin resistance in obesity. A new study reports that a subpopulation of ATMs, TIM4
+
resident ATMs, modulate adipocyte size via platelet-derived growth factor-CC production during development and diet-induced adipose tissue expansion. |
| doi_str_mv | 10.1038/s41574-021-00554-6 |
| format | Article |
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| subjects | 631/443/319 692/699/2743/393 Adipocytes Adipose tissue Body fat Endocrinology Inflammation Insects Insulin Insulin resistance Lipids Macrophages Medicine Medicine & Public Health Metabolism News & Views news-and-views Nutritional status Obesity Platelet-derived growth factor Regulation Roles Stem cells Thermogenesis Tumor necrosis factor-TNF Vascular endothelial growth factor |
| title | TIM4+ adipose tissue-resident macrophages: new modulators of adiposity |
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