Inflammatory Myositis in a Patient With Melanoma

Inflammatory Myositis in a Patient With Melanoma

A 47-year-old man with melanoma presented with 1 week of low-grade fevers, myalgias, elevated creatine kinase levels, and proximal muscle weakness. He previously underwent amputation of a finger and began adjuvant nivolumab for stage IIIC melanoma. One week later, he developed fevers, myalgias, dark...

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2021-09, Vol.326 (9), p.865-866
Hauptverfasser: Maheswaranathan, Mithu, Khouri, Michel G, Weinmann, Sophia C
Format: Artikel
Sprache:eng
Schlagworte:
Amputation
Creatine
Creatine kinase
Inflammation
Inflammatory diseases
Kinases
Melanoma
Muscles
Musculoskeletal diseases
Myositis
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Zusammenfassung:A 47-year-old man with melanoma presented with 1 week of low-grade fevers, myalgias, elevated creatine kinase levels, and proximal muscle weakness. He previously underwent amputation of a finger and began adjuvant nivolumab for stage IIIC melanoma. One week later, he developed fevers, myalgias, dark urine, weakness, and difficulty walking. What is the diagnosis and what would you do next?
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2021.9025