Comparison of seven heterophile antibody assays for laboratory diagnosis of infectious mononucleosis in pediatric patients

Heterophile antibody assays have been used to aid the diagnosis of infectious mononucleosis caused by the Epstein‐Barr virus. Seven commercially available assays currently widely utilized in clinical laboratories were compared in this study. Variable performance characteristics and assay times are o...

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Veröffentlicht in:	Journal of medical virology 2021-11, Vol.93 (11), p.6404-6407
Hauptverfasser:	Wei, Sharon, Huang, Wei, Farah, Mohamed, Khanolkar, Aaruni, Zheng, Xiaotian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies Antibodies, Heterophile - blood Antibodies, Heterophile - immunology Antibodies, Viral - blood Assaying Child Clinical Laboratory Techniques - methods Clinical Laboratory Techniques - standards Diagnosis EBV Epstein-Barr virus Epstein-Barr Virus Infections - blood Epstein-Barr Virus Infections - diagnosis heterophile antibody Humans Immunoglobulin M - blood Infectious mononucleosis Infectious Mononucleosis - blood Infectious Mononucleosis - diagnosis Infectious Mononucleosis - immunology Laboratories Medical laboratories Mononucleosis Pediatrics Reagent Kits, Diagnostic - standards Virology Young Adult
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Beschreibung
Zusammenfassung:	Heterophile antibody assays have been used to aid the diagnosis of infectious mononucleosis caused by the Epstein‐Barr virus. Seven commercially available assays currently widely utilized in clinical laboratories were compared in this study. Variable performance characteristics and assay times are observed, and these pieces of data may assist clinical laboratories in assay selection and result interpretation.
ISSN:	0146-6615 1096-9071
DOI:	10.1002/jmv.27254