Decreased ventricular size and mass mediate the reduced exercise capacity in adolescents and adults born premature

Decreased ventricular size and mass mediate the reduced exercise capacity in adolescents and adults born premature

Premature birth is associated with lower levels of cardiorespiratory fitness (CRF) but the underlying mechanisms responsible remain unclear. This study assessed whether differences in cardiac morphology or function mediate differences in CRF among adolescents and young adults born preterm. Adolescen...

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Veröffentlicht in:Early human development 2021-09, Vol.160, p.105426-105426, Article 105426
Hauptverfasser: McKay, Lauren, Goss, Kara N., Haraldsdottir, Kristin, Beshish, Arij G., Barton, Gregory P., Palta, Mari, Chesler, Naomi C., François, Christopher J., Wieben, Oliver, Macdonald, Jacob A., Eldridge, Marlowe W., Watson, Andrew M.
Format: Artikel
Sprache:eng
Schlagworte:
Blood pressure
Cardiac function
Cardiac structure
Cardiovascular health
Exercise capacity
Preterm birth
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Zusammenfassung:Premature birth is associated with lower levels of cardiorespiratory fitness (CRF) but the underlying mechanisms responsible remain unclear. This study assessed whether differences in cardiac morphology or function mediate differences in CRF among adolescents and young adults born preterm. Adolescents and young adults born moderately to extremely premature (gestational age ≤ 32 weeks or birth weight 
ISSN:0378-3782
1872-6232
DOI:10.1016/j.earlhumdev.2021.105426