Non‐malignant portal vein thrombosis in a cohort of cirrhotic patients: Incidence and risk factors

Aim Non‐malignant portal vein thrombosis (PVT) is a complication of liver cirrhosis. The aim of this study was to evaluate the annual incidence of PVT and related risk factors. Methods We retrospectively reviewed clinical, laboratory, and radiological data collected prospectively from September 2016...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hepatology research 2021-10, Vol.51 (10), p.1064-1072
Hauptverfasser: Lopez‐Gomez, Marta, Llop, Elba, Puente, Angela, Hernández Conde, Marta, Ruiz, Patricia, Alvárez, Silvia, Martínez, Jose Luis, Abad, Javier, Fernández, Natalia, Perelló, Christie, Fernández‐Carrillo, Carlos, Ferre, Carlos, Trapero, Maria, Fraga, Enrique, Crespo, Javier, Calleja Panero, Jose Luis
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Aim Non‐malignant portal vein thrombosis (PVT) is a complication of liver cirrhosis. The aim of this study was to evaluate the annual incidence of PVT and related risk factors. Methods We retrospectively reviewed clinical, laboratory, and radiological data collected prospectively from September 2016 to September 2017. A follow‐up of 36 months was performed in a subset of patients to determine the cumulative incidence of PVT and related complications. Results The study included 567 patients. The incidence of PVT at 12, 24, and 36 months was 3.7%, 0.8%, and 1.4%, respectively. Patients with PVT were compared with patients without PVT, and showed differences in albumin (p = 0.04), aspartate aminotransferase (p = 0.04), hemoglobin (p = 0.01), and prothrombin activity (p = 0.01). The presence of hydropic decompensation (57.1% vs. 30.1%; p 0.004), gastroesophageal varices (76.2% vs. 39.5%; p = 0.05), variceal bleeding (52.4% vs. 22.7%; p 
ISSN:1386-6346
1872-034X
DOI:10.1111/hepr.13703