Cyclodextrins as carriers for volatile aroma compounds: A review

Cyclodextrins (CDs) are edible and biocompatible natural cyclic compounds that can encapsulate essential oils, flavours, volatile aroma compounds, and other substances. Complexation with CD-based materials improves the solubility and stability of volatile compounds and protects the bioactivity of the core materials. Therefore, the development of CD/volatile compound nanosystems is a key research area in the food, cosmetic, and pharmaceutical industries. This review briefly introduces the main types of natural CD; preparation methods of CD-based materials as carriers for aromatic substances or essential oils; characterisation methods used to calculate the interaction between CDs and volatile aroma compounds; molecular docking and simulation methods; and the application of CD-based nanosystems in different industries. The review aims to provide guidance for relevant practitioners in selecting appropriate CD materials and characterisation methods. •Several kinds of cyclodextrin polymer nanosystems were introduced.•Preparation and application of cyclodextrin microcrystals as Pickering emulsion•Research disciplines and methods involved in the interaction between cyclodextrin and volatile aroma compounds•Potential application of cyclodextrin volatile flavour compounds in various fields