Effects of fasting on skeletal muscles and body fat of adult and old C57BL/6J mice
Fasting improves metabolic health, but is also associated with loss of lean body mass. We investigated if old mice are less resistant to fasting-induce muscle wasting than adult mice. We compared changes in skeletal muscles and fat distribution in C57BL/6J mice subjected to 48-hour fasting at adult...
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Veröffentlicht in: | Experimental gerontology 2021-09, Vol.152, p.111474-111474, Article 111474 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Fasting improves metabolic health, but is also associated with loss of lean body mass. We investigated if old mice are less resistant to fasting-induce muscle wasting than adult mice. We compared changes in skeletal muscles and fat distribution in C57BL/6J mice subjected to 48-hour fasting at adult (6-month old) or old (24-month old) age. Old mice lost less weight (11.9 ± 1.5 vs 16.9 ± 2.8%, p |
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ISSN: | 0531-5565 1873-6815 |
DOI: | 10.1016/j.exger.2021.111474 |