Superiority of CRP-albumin-lymphocyte index (CALLY index) as a non-invasive prognostic biomarker after hepatectomy for hepatocellular carcinoma

Superiority of CRP-albumin-lymphocyte index (CALLY index) as a non-invasive prognostic biomarker after hepatectomy for hepatocellular carcinoma

We aimed to investigate whether a novel biomarker incorporating albumin, lymphocytes, and CRP can predict the prognosis for hepatocellular carcinoma (HCC) after hepatectomy. Between January 2011 and December 2013, 384 patients who underwent hepatectomy in four university hospitals in Japan were inve...

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Veröffentlicht in:HPB (Oxford, England) England), 2022-01, Vol.24 (1), p.101-115
Hauptverfasser: Iida, Hiroya, Tani, Masaji, Komeda, Koji, Nomi, Takeo, Matsushima, Hideyuki, Tanaka, Shogo, Ueno, Masaki, Nakai, Takuya, Maehira, Hiromitsu, Mori, Haruki, Matsui, Kosuke, Hirokawa, Fumitoshi, Kaibori, Masaki, Kubo, Shoji
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
C-Reactive Protein
Carcinoma, Hepatocellular
Hepatectomy - adverse effects
Humans
Liver Neoplasms
Lymphocytes
Prognosis
Retrospective Studies
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Zusammenfassung:We aimed to investigate whether a novel biomarker incorporating albumin, lymphocytes, and CRP can predict the prognosis for hepatocellular carcinoma (HCC) after hepatectomy. Between January 2011 and December 2013, 384 patients who underwent hepatectomy in four university hospitals in Japan were investigated as a discovery cohort. The CRP-Albumin-Lymphocyte (CALLY index) was defined as (Albumin × Lymphocyte)/(CRP × 104). Patients with a CALLY index ≥5 (n = 200) were compared to those with an index
ISSN:1365-182X
1477-2574
DOI:10.1016/j.hpb.2021.06.414