Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities
Lipopeptides biosurfactants (BioS) are natural surface-active compounds produced by a variety of microorganisms. They have great interest in environmental, biomedical and agro-industrial fields. However their large-scale application and production is limited by the cost of culture media and the low...
Gespeichert in:
| Veröffentlicht in: | Bioprocess and biosystems engineering 2021-11, Vol.44 (11), p.2315-2330 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2330 |
|---|---|
| container_issue | 11 |
| container_start_page | 2315 |
| container_title | Bioprocess and biosystems engineering |
| container_volume | 44 |
| creator | Mnif, Inès Bouallegue, Amir Mekki, Salwa Ghribi, Dhouha |
| description | Lipopeptides biosurfactants (BioS) are natural surface-active compounds produced by a variety of microorganisms. They have great interest in environmental, biomedical and agro-industrial fields. However their large-scale application and production is limited by the cost of culture media and the low yield of production. Therefore, the improvement of the production yields and the development of efficient and cost-effective bioprocess became of a great interest. In this aim, we applied the response surface method to optimize an economic BioS production by a newly isolated strain
Bacillus mojavensis
BI2 on date Juice called “Luegmi” as unique carbon and nitrogen source. Using a Box-Bhenken design, we studied the effect of three independent variables on lipopeptide production; Leugmi concentration, Na
2
HPO
4
and incubation time. The results of this study showed that Leugmi concentration at 25%, Na
2
HPO
4
at 0.1% and incubation time of 24 h were optimal conditions for BioS production, with a maximum Surface Tension (ST) decreasing capacity of 55% corresponding to 27 mN/m and an Oil Dispersing Activity (ODA) of 30 cm
2
corresponding to a diameter of 6 cm. Preliminary characterization of the BioS produced on Luegmi by UV-Spectra and Thin Layer Chromatography showed its lipopeptide nature. Physic-chemical characterization of the produced lipopeptide on Leugmi showed its great surface activities and stabilities at different pH, temperature and salts concentration. The results of this study suggested that Leugmi, an agricultural byproducts can be used as a low-cost substrate to enhance the yield of lipopeptide BioS with great surface activities for potential environmental application. |
| doi_str_mv | 10.1007/s00449-021-02606-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2550269090</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2550269090</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-103f3a48a34c5fa336d9466672a8a015c6fef0057feceb7af66ef7e84ebee5653</originalsourceid><addsrcrecordid>eNp9kcFu1DAQhi0EoqXwAhyQJS5cAnYS2wk3WrVQqRIX4Bp5nXHrVRIHj1NpeUFei1nSgMSBg2VL_uabsX_GXkrxVgph3qEQdd0WopS0tNCFecROpZaqMFqox9tZtfKEPUPcCyFVU4qn7KSqy1rqVp-yn9_sEFP4YXOIE4-e9zYD3y_BAd8deL4DPqfYL267H8IcZ5hz6AkIEZfkrct2ynjkLT-3LgzDgnyMe3sPEwbk59clx5xsmN4fa0joAJFHsoxbaypOgHOcEPgqBT5Cvot9HOItmaeeHEt_OA6xAdQ53IccAJ-zJ94OCC8e9jP29eryy8Wn4ubzx-uLDzeFq4zKhRSVr2zd2Kp2ytuq0n1ba61NaRtL3-O0By-EMh4c7Iz1WoM30NSwA1BaVWfszeqlR3xfAHM3BnQwDHaCuGBXKkVZtKIVhL7-B93HJU00HVFGS6Fk3RBVrpRLETGB7-YURpsOnRTdMeZujbmjmLvfMXeGil49qJfdCP2fki1XAqoVQLqabiH97f0f7S8CD7iI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2576105148</pqid></control><display><type>article</type><title>Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Mnif, Inès ; Bouallegue, Amir ; Mekki, Salwa ; Ghribi, Dhouha</creator><creatorcontrib>Mnif, Inès ; Bouallegue, Amir ; Mekki, Salwa ; Ghribi, Dhouha</creatorcontrib><description>Lipopeptides biosurfactants (BioS) are natural surface-active compounds produced by a variety of microorganisms. They have great interest in environmental, biomedical and agro-industrial fields. However their large-scale application and production is limited by the cost of culture media and the low yield of production. Therefore, the improvement of the production yields and the development of efficient and cost-effective bioprocess became of a great interest. In this aim, we applied the response surface method to optimize an economic BioS production by a newly isolated strain
Bacillus mojavensis
BI2 on date Juice called “Luegmi” as unique carbon and nitrogen source. Using a Box-Bhenken design, we studied the effect of three independent variables on lipopeptide production; Leugmi concentration, Na
2
HPO
4
and incubation time. The results of this study showed that Leugmi concentration at 25%, Na
2
HPO
4
at 0.1% and incubation time of 24 h were optimal conditions for BioS production, with a maximum Surface Tension (ST) decreasing capacity of 55% corresponding to 27 mN/m and an Oil Dispersing Activity (ODA) of 30 cm
2
corresponding to a diameter of 6 cm. Preliminary characterization of the BioS produced on Luegmi by UV-Spectra and Thin Layer Chromatography showed its lipopeptide nature. Physic-chemical characterization of the produced lipopeptide on Leugmi showed its great surface activities and stabilities at different pH, temperature and salts concentration. The results of this study suggested that Leugmi, an agricultural byproducts can be used as a low-cost substrate to enhance the yield of lipopeptide BioS with great surface activities for potential environmental application.</description><identifier>ISSN: 1615-7591</identifier><identifier>EISSN: 1615-7605</identifier><identifier>DOI: 10.1007/s00449-021-02606-7</identifier><identifier>PMID: 34241696</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Bacillus - metabolism ; Bacillus mojavensis ; Biosurfactants ; Biotechnology ; Chemistry ; Chemistry and Materials Science ; Chromatography, Thin Layer ; Culture media ; Environmental Engineering/Biotechnology ; Food Science ; Fruit and Vegetable Juices - analysis ; Hydrogen-Ion Concentration ; Independent variables ; Industrial and Production Engineering ; Industrial Chemistry/Chemical Engineering ; Lipopeptides ; Lipopeptides - biosynthesis ; Microorganisms ; Optimization ; Phoeniceae - chemistry ; Research Paper ; Response surface methodology ; Salinity ; Salts ; Sodium hydrogen phosphate ; Spectrophotometry, Ultraviolet ; Spectroscopy, Fourier Transform Infrared ; Substrates ; Surface Tension ; Surface-Active Agents - metabolism ; Surfactants ; Temperature ; Thin layer chromatography</subject><ispartof>Bioprocess and biosystems engineering, 2021-11, Vol.44 (11), p.2315-2330</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-103f3a48a34c5fa336d9466672a8a015c6fef0057feceb7af66ef7e84ebee5653</citedby><cites>FETCH-LOGICAL-c375t-103f3a48a34c5fa336d9466672a8a015c6fef0057feceb7af66ef7e84ebee5653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00449-021-02606-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00449-021-02606-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34241696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mnif, Inès</creatorcontrib><creatorcontrib>Bouallegue, Amir</creatorcontrib><creatorcontrib>Mekki, Salwa</creatorcontrib><creatorcontrib>Ghribi, Dhouha</creatorcontrib><title>Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities</title><title>Bioprocess and biosystems engineering</title><addtitle>Bioprocess Biosyst Eng</addtitle><addtitle>Bioprocess Biosyst Eng</addtitle><description>Lipopeptides biosurfactants (BioS) are natural surface-active compounds produced by a variety of microorganisms. They have great interest in environmental, biomedical and agro-industrial fields. However their large-scale application and production is limited by the cost of culture media and the low yield of production. Therefore, the improvement of the production yields and the development of efficient and cost-effective bioprocess became of a great interest. In this aim, we applied the response surface method to optimize an economic BioS production by a newly isolated strain
Bacillus mojavensis
BI2 on date Juice called “Luegmi” as unique carbon and nitrogen source. Using a Box-Bhenken design, we studied the effect of three independent variables on lipopeptide production; Leugmi concentration, Na
2
HPO
4
and incubation time. The results of this study showed that Leugmi concentration at 25%, Na
2
HPO
4
at 0.1% and incubation time of 24 h were optimal conditions for BioS production, with a maximum Surface Tension (ST) decreasing capacity of 55% corresponding to 27 mN/m and an Oil Dispersing Activity (ODA) of 30 cm
2
corresponding to a diameter of 6 cm. Preliminary characterization of the BioS produced on Luegmi by UV-Spectra and Thin Layer Chromatography showed its lipopeptide nature. Physic-chemical characterization of the produced lipopeptide on Leugmi showed its great surface activities and stabilities at different pH, temperature and salts concentration. The results of this study suggested that Leugmi, an agricultural byproducts can be used as a low-cost substrate to enhance the yield of lipopeptide BioS with great surface activities for potential environmental application.</description><subject>Bacillus - metabolism</subject><subject>Bacillus mojavensis</subject><subject>Biosurfactants</subject><subject>Biotechnology</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chromatography, Thin Layer</subject><subject>Culture media</subject><subject>Environmental Engineering/Biotechnology</subject><subject>Food Science</subject><subject>Fruit and Vegetable Juices - analysis</subject><subject>Hydrogen-Ion Concentration</subject><subject>Independent variables</subject><subject>Industrial and Production Engineering</subject><subject>Industrial Chemistry/Chemical Engineering</subject><subject>Lipopeptides</subject><subject>Lipopeptides - biosynthesis</subject><subject>Microorganisms</subject><subject>Optimization</subject><subject>Phoeniceae - chemistry</subject><subject>Research Paper</subject><subject>Response surface methodology</subject><subject>Salinity</subject><subject>Salts</subject><subject>Sodium hydrogen phosphate</subject><subject>Spectrophotometry, Ultraviolet</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Substrates</subject><subject>Surface Tension</subject><subject>Surface-Active Agents - metabolism</subject><subject>Surfactants</subject><subject>Temperature</subject><subject>Thin layer chromatography</subject><issn>1615-7591</issn><issn>1615-7605</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kcFu1DAQhi0EoqXwAhyQJS5cAnYS2wk3WrVQqRIX4Bp5nXHrVRIHj1NpeUFei1nSgMSBg2VL_uabsX_GXkrxVgph3qEQdd0WopS0tNCFecROpZaqMFqox9tZtfKEPUPcCyFVU4qn7KSqy1rqVp-yn9_sEFP4YXOIE4-e9zYD3y_BAd8deL4DPqfYL267H8IcZ5hz6AkIEZfkrct2ynjkLT-3LgzDgnyMe3sPEwbk59clx5xsmN4fa0joAJFHsoxbaypOgHOcEPgqBT5Cvot9HOItmaeeHEt_OA6xAdQ53IccAJ-zJ94OCC8e9jP29eryy8Wn4ubzx-uLDzeFq4zKhRSVr2zd2Kp2ytuq0n1ba61NaRtL3-O0By-EMh4c7Iz1WoM30NSwA1BaVWfszeqlR3xfAHM3BnQwDHaCuGBXKkVZtKIVhL7-B93HJU00HVFGS6Fk3RBVrpRLETGB7-YURpsOnRTdMeZujbmjmLvfMXeGil49qJfdCP2fki1XAqoVQLqabiH97f0f7S8CD7iI</recordid><startdate>20211101</startdate><enddate>20211101</enddate><creator>Mnif, Inès</creator><creator>Bouallegue, Amir</creator><creator>Mekki, Salwa</creator><creator>Ghribi, Dhouha</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20211101</creationdate><title>Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities</title><author>Mnif, Inès ; Bouallegue, Amir ; Mekki, Salwa ; Ghribi, Dhouha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-103f3a48a34c5fa336d9466672a8a015c6fef0057feceb7af66ef7e84ebee5653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Bacillus - metabolism</topic><topic>Bacillus mojavensis</topic><topic>Biosurfactants</topic><topic>Biotechnology</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chromatography, Thin Layer</topic><topic>Culture media</topic><topic>Environmental Engineering/Biotechnology</topic><topic>Food Science</topic><topic>Fruit and Vegetable Juices - analysis</topic><topic>Hydrogen-Ion Concentration</topic><topic>Independent variables</topic><topic>Industrial and Production Engineering</topic><topic>Industrial Chemistry/Chemical Engineering</topic><topic>Lipopeptides</topic><topic>Lipopeptides - biosynthesis</topic><topic>Microorganisms</topic><topic>Optimization</topic><topic>Phoeniceae - chemistry</topic><topic>Research Paper</topic><topic>Response surface methodology</topic><topic>Salinity</topic><topic>Salts</topic><topic>Sodium hydrogen phosphate</topic><topic>Spectrophotometry, Ultraviolet</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Substrates</topic><topic>Surface Tension</topic><topic>Surface-Active Agents - metabolism</topic><topic>Surfactants</topic><topic>Temperature</topic><topic>Thin layer chromatography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mnif, Inès</creatorcontrib><creatorcontrib>Bouallegue, Amir</creatorcontrib><creatorcontrib>Mekki, Salwa</creatorcontrib><creatorcontrib>Ghribi, Dhouha</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Bioprocess and biosystems engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mnif, Inès</au><au>Bouallegue, Amir</au><au>Mekki, Salwa</au><au>Ghribi, Dhouha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities</atitle><jtitle>Bioprocess and biosystems engineering</jtitle><stitle>Bioprocess Biosyst Eng</stitle><addtitle>Bioprocess Biosyst Eng</addtitle><date>2021-11-01</date><risdate>2021</risdate><volume>44</volume><issue>11</issue><spage>2315</spage><epage>2330</epage><pages>2315-2330</pages><issn>1615-7591</issn><eissn>1615-7605</eissn><abstract>Lipopeptides biosurfactants (BioS) are natural surface-active compounds produced by a variety of microorganisms. They have great interest in environmental, biomedical and agro-industrial fields. However their large-scale application and production is limited by the cost of culture media and the low yield of production. Therefore, the improvement of the production yields and the development of efficient and cost-effective bioprocess became of a great interest. In this aim, we applied the response surface method to optimize an economic BioS production by a newly isolated strain
Bacillus mojavensis
BI2 on date Juice called “Luegmi” as unique carbon and nitrogen source. Using a Box-Bhenken design, we studied the effect of three independent variables on lipopeptide production; Leugmi concentration, Na
2
HPO
4
and incubation time. The results of this study showed that Leugmi concentration at 25%, Na
2
HPO
4
at 0.1% and incubation time of 24 h were optimal conditions for BioS production, with a maximum Surface Tension (ST) decreasing capacity of 55% corresponding to 27 mN/m and an Oil Dispersing Activity (ODA) of 30 cm
2
corresponding to a diameter of 6 cm. Preliminary characterization of the BioS produced on Luegmi by UV-Spectra and Thin Layer Chromatography showed its lipopeptide nature. Physic-chemical characterization of the produced lipopeptide on Leugmi showed its great surface activities and stabilities at different pH, temperature and salts concentration. The results of this study suggested that Leugmi, an agricultural byproducts can be used as a low-cost substrate to enhance the yield of lipopeptide BioS with great surface activities for potential environmental application.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34241696</pmid><doi>10.1007/s00449-021-02606-7</doi><tpages>16</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1615-7591 |
| ispartof | Bioprocess and biosystems engineering, 2021-11, Vol.44 (11), p.2315-2330 |
| issn | 1615-7591 1615-7605 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2550269090 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Bacillus - metabolism Bacillus mojavensis Biosurfactants Biotechnology Chemistry Chemistry and Materials Science Chromatography, Thin Layer Culture media Environmental Engineering/Biotechnology Food Science Fruit and Vegetable Juices - analysis Hydrogen-Ion Concentration Independent variables Industrial and Production Engineering Industrial Chemistry/Chemical Engineering Lipopeptides Lipopeptides - biosynthesis Microorganisms Optimization Phoeniceae - chemistry Research Paper Response surface methodology Salinity Salts Sodium hydrogen phosphate Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Substrates Surface Tension Surface-Active Agents - metabolism Surfactants Temperature Thin layer chromatography |
| title | Valorization of date juice by the production of lipopeptide biosurfactants by a Bacillus mojavensis BI2 strain: bioprocess optimization by response surface methodology and study of surface activities |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T05%3A54%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Valorization%20of%20date%20juice%20by%20the%20production%20of%20lipopeptide%20biosurfactants%20by%20a%20Bacillus%20mojavensis%20BI2%20strain:%20bioprocess%20optimization%20by%20response%20surface%20methodology%20and%20study%20of%20surface%20activities&rft.jtitle=Bioprocess%20and%20biosystems%20engineering&rft.au=Mnif,%20In%C3%A8s&rft.date=2021-11-01&rft.volume=44&rft.issue=11&rft.spage=2315&rft.epage=2330&rft.pages=2315-2330&rft.issn=1615-7591&rft.eissn=1615-7605&rft_id=info:doi/10.1007/s00449-021-02606-7&rft_dat=%3Cproquest_cross%3E2550269090%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2576105148&rft_id=info:pmid/34241696&rfr_iscdi=true |