Finding the needle in the haystack: the diagnostic accuracy of the faecal immunochemical test for colorectal cancer in younger symptomatic patients

Finding the needle in the haystack: the diagnostic accuracy of the faecal immunochemical test for colorectal cancer in younger symptomatic patients

Aim Detection of early onset colorectal cancer is challenging, and remains a rare diagnosis amongst younger people with gastrointestinal symptoms. We investigated whether faecal immunochemical testing (FIT) could identify younger patients at higher risk of colorectal cancer or serious bowel disease...

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Veröffentlicht in:Colorectal disease 2021-10, Vol.23 (10), p.2539-2549
Hauptverfasser: D’Souza, Nigel, Monahan, Kevin, Benton, Sally C., Wilde, Lisa, Abulafi, Muti, Delisle, Theo Georgiou, West, Nicholas, Mitchell, Toni, Ziprin, Paul, Chen, Michelle, Dzakpasu‐Amevor, Anthonette, Nangendo, Christine, Nisar, Pasha, Gercek, Yuksel, Austin, Mark, Hall, Nigel, Gupta, Robin, Bhardway, Rakesh, Oglesby, Arabis, Khan, Usman, Khan, Nasser, Mangam, Sudhakar, Cope, Alexandra, Thomas, Isobel, Ramage, John, Pugh, Mark, Lal, Roshan, Agarwal, Tushar, Jenkins, Ian, Hill, Mark, Wegstapel, Henk, Hariharan, Vimal, Kurrimboccus, Salim, Clarke, Andrew, Dobson, Tracey, Ellul, Joseph, Webb, Hayley, Faulkner, Gemma, Wijeyekoon, Sanjaya, Smart, Neil, Stebbing, John, Epstein, Jonathan, Branagan, Graham, Foley, Stephen, Bateman, Andrew, Levy, Bruce, Day, Andrew, Lenehan, Fionnuala, Ward, Nicholas, Wacklin, Lisa, Mackenzie, Naomi
Format: Artikel
Sprache:eng
Schlagworte:
Accuracy
Bowel disease
Cancer
colonoscopy
Colorectal cancer
Colorectal carcinoma
colorectal neoplasms
diagnostic accuracy
faecal immunochemical test
FIT
Hemoglobin
Inflammatory bowel diseases
Intestine
Investigations
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Zusammenfassung:Aim Detection of early onset colorectal cancer is challenging, and remains a rare diagnosis amongst younger people with gastrointestinal symptoms. We investigated whether faecal immunochemical testing (FIT) could identify younger patients at higher risk of colorectal cancer or serious bowel disease including colorectal cancer, inflammatory bowel disease or advanced adenomas. Methods A subgroup analysis was performed of symptomatic patients under 50 years of age (
ISSN:1462-8910
1463-1318
DOI:10.1111/codi.15786