Performance of the IBIS/Tyrer‐Cuzick model of breast cancer risk by race and ethnicity in the Women's Health Initiative

Performance of the IBIS/Tyrer‐Cuzick model of breast cancer risk by race and ethnicity in the Women's Health Initiative

BACKGROUND The IBIS/Tyrer‐Cuzick model is used clinically to guide breast cancer screening and prevention, but was developed primarily in non‐Hispanic White women. Little is known about its long‐term performance in a racially/ethnically diverse population. METHODS The Women's Health Initiative...

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Veröffentlicht in:Cancer 2021-10, Vol.127 (20), p.3742-3750
Hauptverfasser: Kurian, Allison W., Hughes, Elisha, Simmons, Timothy, Bernhisel, Ryan, Probst, Braden, Meek, Stephanie, Caswell‐Jin, Jennifer L., John, Esther M., Lanchbury, Jerry S., Slavin, Thomas P., Wagner, Susanne, Gutin, Alexander, Rohan, Thomas E., Shadyab, Aladdin H., Manson, JoAnn E., Lane, Dorothy, Chlebowski, Rowan T., Stefanick, Marcia L.
Format: Artikel
Sprache:eng
Schlagworte:
Aged, 80 and over
Breast cancer
breast cancer risk
Breast Neoplasms - diagnosis
Breast Neoplasms - epidemiology
Breast Neoplasms - genetics
Calibration
Cancer screening
Discrimination
Ethnicity
Ethnicity - genetics
Female
Genetics
Health risks
Hispanic people
Humans
IBIS/Tyrer‐Cuzick
Mastectomy
Medical screening
Menarche
Menopause
Minority & ethnic groups
model performance
Nucleotides
Oncology
Ovarian cancer
Polymorphism
Post-menopause
Race
race/ethnicity
Risk analysis
Risk Assessment
Risk factors
Simulation
Single-nucleotide polymorphism
Women's Health
Womens health
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Zusammenfassung:BACKGROUND The IBIS/Tyrer‐Cuzick model is used clinically to guide breast cancer screening and prevention, but was developed primarily in non‐Hispanic White women. Little is known about its long‐term performance in a racially/ethnically diverse population. METHODS The Women's Health Initiative study enrolled postmenopausal women from 1993‐1998. Women were included who were aged
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.33767