Factors associated with negative 99mTc-MIBI scanning in patients with primary hyperparathyroidism

Factors associated with negative 99mTc-MIBI scanning in patients with primary hyperparathyroidism

The objective was to evaluate the clinical and biological factors associated with negative 99mTc-MIBI scanning in patients with primary hyperparathyroidism (PHPT). A retrospective observational study was designed in 195 patients (mean age: 59.2 ± 13.0 years; 77% woman) with PHPT (calcium: 11,3 ± 1,1...

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Veröffentlicht in:Revista Española de medicina nuclear e imagen molecular (English ed.) 2021-07, Vol.40 (4), p.222-228
Hauptverfasser: Carral, F., Jiménez, A.I., Tomé, M., Álvarez, J., Díez, A., Partida, F., Ayala, C.
Format: Artikel
Sprache:eng
Schlagworte:
Adenoma paratiroideo
Fine needle aspiration puncture
Hiperparatiroidismo primario
Hormona paratiroidea
Parathyroid adenoma
Parathyroid hormone
Primary hyperparathyroidism
Punción aspiración con aguja fina
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Zusammenfassung:The objective was to evaluate the clinical and biological factors associated with negative 99mTc-MIBI scanning in patients with primary hyperparathyroidism (PHPT). A retrospective observational study was designed in 195 patients (mean age: 59.2 ± 13.0 years; 77% woman) with PHPT (calcium: 11,3 ± 1,1 mg/dl and PTH: 218 ± 295 pg/ml) studied in endocrinology setting between 2013 and 2020. An univariate and multivariate analysis was made to evaluate the clinical and biological factors associated with negative 99mTc-MIBI scanning. 50 patients (26%) with negative 99mTc-MIBI scanning had lower PTH levels (146 ± 98 vs. 244 ± 334; p 
ISSN:2253-8089
2253-8089
DOI:10.1016/j.remnie.2021.01.007