CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy. The network consists of universities, academic institutes, regional sequencing centres a...

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Veröffentlicht in:Genome Biology 2021-07, Vol.22 (1), p.196-196, Article 196
Hauptverfasser: Nicholls, Samuel M, Poplawski, Radoslaw, Bull, Matthew J, Underwood, Anthony, Chapman, Michael, Abu-Dahab, Khalil, Taylor, Ben, Colquhoun, Rachel M, Rowe, Will P M, Jackson, Ben, Hill, Verity, O'Toole, Áine, Rey, Sara, Southgate, Joel, Amato, Roberto, Livett, Rich, Gonçalves, Sónia, Harrison, Ewan M, Peacock, Sharon J, Aanensen, David M, Rambaut, Andrew, Connor, Thomas R, Loman, Nicholas J
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Sprache:eng
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Zusammenfassung:In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy. The network consists of universities, academic institutes, regional sequencing centres and the four UK Public Health Agencies. We describe the development and deployment of CLIMB-COVID, an encompassing digital infrastructure to address the challenge of collecting and integrating both genomic sequencing data and sample-associated metadata produced across the COG-UK network.
ISSN:1474-760X
1474-7596
1474-760X
DOI:10.1186/s13059-021-02395-y