Delivered dose–effect analysis of radiation induced rib fractures after thoracic SBRT

Delivered dose–effect analysis of radiation induced rib fractures after thoracic SBRT

•First investigation of the delivered dose to the ribs in 437 NSCLC SBRT patients.•Maximum doses best predict rib fractures.•The maximum delivered dose was significantly lower than the maximum planned dose.•Difference between delivered and planned NTCP models was

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Bibliographische Detailangaben
Veröffentlicht in:Radiotherapy and oncology 2021-09, Vol.162, p.18-25
Hauptverfasser: Juan-Cruz, Celia, Stam, Barbara, Belderbos, José, Sonke, Jan-Jakob
Format: Artikel
Sprache:eng
Schlagworte:
Dose accumulation
Lung cancer
NTCP
Rib fracture
SBRT
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Beschreibung
Zusammenfassung:•First investigation of the delivered dose to the ribs in 437 NSCLC SBRT patients.•Maximum doses best predict rib fractures.•The maximum delivered dose was significantly lower than the maximum planned dose.•Difference between delivered and planned NTCP models was
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2021.06.028