Nonhuman primate models for SARS-CoV-2 Research: Managing demand for specific-pathogen-free (SPF) animals

The SARS-CoV-2/COVID-19 pandemic has significantly increased the demand for specific-pathogen-free (SPF) nonhuman primates (NHPs) for development of vaccines and therapeutics, thus straining the supply of these animals for biomedical research studies. Non-SPF animals, which are available in greater...

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Veröffentlicht in:	Lab animal 2021-08, Vol.50 (8), p.200-201
Hauptverfasser:	Contreras, Miguel A., Arnegard, Matthew E., Chang, Michael C., Hild, Sheri, Grieder, Franziska, Murphy, Stephanie J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/1348 692/308/1426 692/308/2778 Analysis Animal experimentation Animal Models Animal models in research Animals Antiviral agents Biomedical and Life Sciences Comment COVID-19 Disease Models, Animal Evaluation Humans Life Sciences Macaca mulatta Pathogens Primates SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Specific Pathogen-Free Organisms Veterinary Medicine/Veterinary Science
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Beschreibung
Zusammenfassung:	The SARS-CoV-2/COVID-19 pandemic has significantly increased the demand for specific-pathogen-free (SPF) nonhuman primates (NHPs) for development of vaccines and therapeutics, thus straining the supply of these animals for biomedical research studies. Non-SPF animals, which are available in greater numbers and include well-characterized primate species, should be considered in lieu of limited SPF animals for appropriate research studies.
ISSN:	0093-7355 1548-4475
DOI:	10.1038/s41684-021-00810-2