Efficacy of brief intervention for harmful and hazardous alcohol use: a systematic review and meta‐analysis of studies from low middle‐income countries

Background and Aims Low and middle‐income countries (LMIC) have a disproportionately higher alcohol‐attributable disease burden, in conjunction with a minimal focus on primary prevention. Screening and brief interventions can be a promising approach to address this problem. This systematic review aimed to perform a qualitative and quantitative synthesis of studies of brief interventions for harmful and hazardous alcohol use in LMIC. Methods Systematic review of randomized controlled trials of brief interventions for harmful and hazardous alcohol identified from four electronic databases, conducted in any country identified as LMIC as per the World Bank. We measured differences in intervention and control groups on risk‐scores using standard screening instruments, the frequency of heavy drinking, the drinking risk‐level, or quality of life and other mental health‐related outcomes. Results A total of 14 studies were included, seven of them from South Africa. On standardized screening instruments, the brief intervention (BI) group had significantly lower scores than controls at 3 months (Hedges’ g = − 0.34, P = 0.04), but the effects did not persist at 6‐ and 12‐month follow‐up (g = − 0.06, P = 0.68 and g = 0.15, P = 0.41, respectively). There was little evidence to suggest that BIs led to changes in the frequency of heavy drinking or change in the risk level of alcohol use. Surprisingly, a single session (g = −0.55, P