Effectiveness of Blood Lipid Management in Patients With Peripheral Artery Disease
Low-density lipoprotein cholesterol (LDL-C) is associated with heightened risk of major adverse cardiovascular events (MACE) and major adverse limb events (MALE) in peripheral artery disease (PAD). Lipid-lowering therapies (LLT) that reduce LDL-C decrease this risk. The authors examined LLT use and...
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Veröffentlicht in: | Journal of the American College of Cardiology 2021-06, Vol.77 (24), p.3016-3027 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Low-density lipoprotein cholesterol (LDL-C) is associated with heightened risk of major adverse cardiovascular events (MACE) and major adverse limb events (MALE) in peripheral artery disease (PAD). Lipid-lowering therapies (LLT) that reduce LDL-C decrease this risk.
The authors examined LLT use and actual achieved LDL-C in PAD.
PAD patients in MarketScan from 2014 to 2018 were identified. Outcomes included LLT use, defined as high-intensity (HI) (high-intensity statin, statin plus ezetimibe, or PCSK9 inhibitor), low-intensity (any other lipid regimen), or no therapy, and follow-up LDL-C. Factors associated with LDL-C |
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ISSN: | 0735-1097 1558-3597 |
DOI: | 10.1016/j.jacc.2021.04.060 |