A base-pair view of interactions between genes and their enhancers

A base-pair view of interactions between genes and their enhancers

A technique reveals how folded chromosomal DNA interacts in the nucleus, providing information at the level of single base pairs. The achievement offers an unprecedented level of detail about how gene activity is regulated. Method monitors 3D genome architecture at a high level of precision.

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Veröffentlicht in:Nature (London) 2021-07, Vol.595 (7865), p.36-37
Hauptverfasser: van Schoonhoven, Anne, Stadhouders, Ralph
Format: Artikel
Sprache:eng
Schlagworte:
631/208/212
631/61
Humanities and Social Sciences
multidisciplinary
News And Views
Science
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Zusammenfassung:A technique reveals how folded chromosomal DNA interacts in the nucleus, providing information at the level of single base pairs. The achievement offers an unprecedented level of detail about how gene activity is regulated. Method monitors 3D genome architecture at a high level of precision.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-021-01494-x