Fluorescent-Oxaboroles: Synthesis and Optical Property by Sugar Recognition

Fluorescent-Oxaboroles: Synthesis and Optical Property by Sugar Recognition

The optical property of fluorescent unit-conjugated aliphatic oxaboroles has been investigated. The oxaboroles provide good fluorescence quantum yields and selective recognition toward D-ribose and D-ribose containing molecules. The molecular recognition induced significant fluorescence quenching. T...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 2021/06/01, Vol.69(6), pp.526-528
Hauptverfasser: Nakano, Misaki, Nakamura, Rikako, Sumida, Yuto, Nagao, Kazunori, Furuyama, Taniyuki, Inagaki, Fuyuhiko, Ohmiya, Hirohisa
Format: Artikel
Sprache:eng
Schlagworte:
Adenine
Boron
D-Ribose
Fluorescence
NAD
Nicotinamide
Nicotinamide adenine dinucleotide
nucleic acid
Optical properties
oxaborole
photo quenching
Recognition
Ribose
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Zusammenfassung:The optical property of fluorescent unit-conjugated aliphatic oxaboroles has been investigated. The oxaboroles provide good fluorescence quantum yields and selective recognition toward D-ribose and D-ribose containing molecules. The molecular recognition induced significant fluorescence quenching. The property of the boroles showed the possibility of the boron-based nicotinamide adenine dinucleotide (NAD) sensor probe.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.c21-00179