Two-photon fluorescence and MR bio-imaging of endogenous H2O2 in the tumor microenvironment using a dual-mode nanoprobe
The dual-mode bio-imaging nanoprobe TP-CQDs@MnO2, based on two-photon carbon quantum dots and MnO2, has been developed for the two-photon fluorescence and MR imaging of endogenous H2O2 in the tumor microenvironment, and it achieved high selectivity, a great signal-to-noise ratio, a limit of detectio...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2021-06, Vol.57 (51), p.6288-6291 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Zhong, Hongmei Yu, Shengrong Li, Bingqian He, Kangdi Li, Dian Wang, Xiao Yong-Xiang, Wu |
| description | The dual-mode bio-imaging nanoprobe TP-CQDs@MnO2, based on two-photon carbon quantum dots and MnO2, has been developed for the two-photon fluorescence and MR imaging of endogenous H2O2 in the tumor microenvironment, and it achieved high selectivity, a great signal-to-noise ratio, a limit of detection (LOD) of 1.425 pM for H2O2, and a two-photon tissue penetration depth of 280 μm. |
| doi_str_mv | 10.1039/d1cc01129d |
| format | Article |
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Yu, Shengrong ; Li, Bingqian ; He, Kangdi ; Li, Dian ; Wang, Xiao ; Yong-Xiang, Wu</creator><creatorcontrib>Zhong, Hongmei ; Yu, Shengrong ; Li, Bingqian ; He, Kangdi ; Li, Dian ; Wang, Xiao ; Yong-Xiang, Wu</creatorcontrib><description>The dual-mode bio-imaging nanoprobe TP-CQDs@MnO2, based on two-photon carbon quantum dots and MnO2, has been developed for the two-photon fluorescence and MR imaging of endogenous H2O2 in the tumor microenvironment, and it achieved high selectivity, a great signal-to-noise ratio, a limit of detection (LOD) of 1.425 pM for H2O2, and a two-photon tissue penetration depth of 280 μm.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/d1cc01129d</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Fluorescence ; Hydrogen peroxide ; Magnetic resonance imaging ; Manganese dioxide ; Penetration depth ; Photons ; Quantum dots ; Selectivity ; Signal to noise ratio ; 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| ispartof | Chemical communications (Cambridge, England), 2021-06, Vol.57 (51), p.6288-6291 |
| issn | 1359-7345 1364-548X |
| language | eng |
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| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Fluorescence Hydrogen peroxide Magnetic resonance imaging Manganese dioxide Penetration depth Photons Quantum dots Selectivity Signal to noise ratio Tumors |
| title | Two-photon fluorescence and MR bio-imaging of endogenous H2O2 in the tumor microenvironment using a dual-mode nanoprobe |
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