Combining biological and chemical diversity

Phage display enables screening of billions of peptides comprised mainly of natural amino acids. Now, a method to attach and encode a range of structurally diverse compounds has been reported. This method can expand the chemical space covered by phage display peptide libraries.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature chemistry 2021-06, Vol.13 (6), p.512-513
1. Verfasser:	Heinis, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/1435 639/638/92/605 Amino acids Analytical Chemistry Biochemistry Biodiversity Chemical compounds Chemistry Chemistry and Materials Science Chemistry/Food Science Diversification Inorganic Chemistry Ligands News & Views news-and-views Organic Chemistry Peptide libraries Peptides Phage display Phages Physical Chemistry Proteins
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Beschreibung
Zusammenfassung:	Phage display enables screening of billions of peptides comprised mainly of natural amino acids. Now, a method to attach and encode a range of structurally diverse compounds has been reported. This method can expand the chemical space covered by phage display peptide libraries.
ISSN:	1755-4330 1755-4349 1755-4349
DOI:	10.1038/s41557-021-00722-1