Prognostic impact of lymph node micrometastasis in patients with gastric cancer

Purpose The clinical significance of lymph node micrometastasis (LNMM) remains controversial in gastric cancer (GC). In this study, we investigated the prognostic impact of LNMM in patients with GC. Methods A total of 624 patients with pathologically lymph node metastasis-negative (pN0) and N1 statu...

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Veröffentlicht in:	Surgery today (Tokyo, Japan) Japan), 2022, Vol.52 (1), p.61-68
Hauptverfasser:	Yamamoto, Atsushi, Shoda, Katsutoshi, Kawaguchi, Yoshihiko, Akaike, Hidenori, Saito, Ryo, Ashizawa, Naoki, Takiguchi, Koichi, Furuya, Shinji, Hosomura, Naohiro, Amemiya, Hidetake, Kawaida, Hiromichi, Sudo, Makoto, Kono, Hiroshi, Mochizuki, Kunio, Ichikawa, Daisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor Female Humans Lymph Nodes - physiology Lymphatic Metastasis - pathology Male Medicine Medicine & Public Health Middle Aged Neoplasm Micrometastasis - pathology Neoplasm Staging Original Article Prognosis Retrospective Studies Stomach Neoplasms - pathology Surgery Surgical Oncology
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Zusammenfassung:	Purpose The clinical significance of lymph node micrometastasis (LNMM) remains controversial in gastric cancer (GC). In this study, we investigated the prognostic impact of LNMM in patients with GC. Methods A total of 624 patients with pathologically lymph node metastasis-negative (pN0) and N1 status (pN1) who underwent gastrectomy between 2004 and 2018 were enrolled in this retrospective study. The diameter of tumor cell clusters in metastatic lymph nodes was measured in 120 patients with pN1 GC. Results Patients with lymph node tumors
ISSN:	0941-1291 1436-2813
DOI:	10.1007/s00595-021-02302-9