Whole-genome sequencing for myeloid disease: one assay to stratify them all?

Whole-genome sequencing for myeloid disease: one assay to stratify them all?

Whole-genome sequencing of samples from patients with myeloid malignancies can enable more accurate risk stratification than is possible with conventional cytogenetics. Research by Duncavage et al. demonstrates that such an approach can now be delivered within several days using a highly streamlined...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature reviews. Clinical oncology 2021-09, Vol.18 (9), p.543-544
Hauptverfasser: Larkin, Karilyn T. M., Byrd, John C.
Format: Artikel
Sprache:eng
Schlagworte:
692/4028/67/1059/602
692/4028/67/1990/283/1897
692/4028/67/69
Cancer
Cytogenetics
DNA sequencing
Genomes
Medicine
Medicine & Public Health
Myeloid cells
News & Views
news-and-views
Nucleotide sequencing
Oncology
Oncology, Experimental
Whole genome sequencing
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Whole-genome sequencing of samples from patients with myeloid malignancies can enable more accurate risk stratification than is possible with conventional cytogenetics. Research by Duncavage et al. demonstrates that such an approach can now be delivered within several days using a highly streamlined and automated workflow.
ISSN:1759-4774
1759-4782
DOI:10.1038/s41571-021-00522-z