Reduced alternative insulin dosing in hyperkalemia: A meta‐analysis of effects on hypoglycemia and potassium reduction
Study Objective Recent studies have identified that reduced alternative intravenous insulin doses, such as 5 units or 0.1 units/kg, may reduce the risk of hypoglycemia compared to standard doses of 10 units in patients treated for hyperkalemia. However, some studies suggest that these alternative do...
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Veröffentlicht in: | Pharmacotherapy 2021-07, Vol.41 (7), p.598-607 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Study Objective
Recent studies have identified that reduced alternative intravenous insulin doses, such as 5 units or 0.1 units/kg, may reduce the risk of hypoglycemia compared to standard doses of 10 units in patients treated for hyperkalemia. However, some studies suggest that these alternative doses may reduce the ability to lower serum potassium. This study was performed to determine the impact of alternative insulin dosing on hypoglycemia and potassium reduction in patients with hyperkalemia.
Design
Meta‐analysis.
Data Source
PubMed/MEDLINE, CENTRAL, Ovid, and ClinicalTrials.gov were searched from inception through November 2020.
Patients
Patients treated with standard (10 units) or alternative ( |
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ISSN: | 0277-0008 1875-9114 |
DOI: | 10.1002/phar.2596 |